Innovación en flu : Oportunidades ...

D-711empresa anónima / Brasil

1421

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En busca de un protector para la tos, resfriados y la gripe estacional

cough, cold, flu, winter disease, OTC, prevention disease products, protection winter ailments

Resultado deseado

An international Pharma products group with offices in Brazil is seeking technologies and approaches that enable long lasting protection from Cough/Cold/Flu/Winter ailments. Suitable technologies or approaches should be able to be used as a 1-off “shot”, or course of treatment and give protection for a significant duration afterwards (i.e. several months or weeks) to offer one of the following benefits:

- Reduced number of coughs, colds, winter ailments
- Reduced severity and or duration of coughs, colds, winter ailments
- Reduced chance of infection when in “high risk” environments (i.e. Airplanes, crowded urban areas)

Suitable technologies or approaches may be physical, chemical or biological. Technologies at all stages of development (Lab testing, clinical testing, commercial products) are of interest.

31/03/13 - El deadline de esta demanda ha caducado

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Detalles de la demanda :

Un grupo internacional de productos farmaceuticos con oficinas en Brasil está buscando tecnologías y enfoques que permitan una protección duradera de las siguientes dolencias: la tos / resfriado / gripe estacional. Las tecnologías buscadas deberían ser capazes de ser utilizadas como un solo curso de tratamiento, tener una protección significativa (es decir, varios meses o semanas) y ofrecer uno de los siguientes beneficios:

- Reducción del número de dolencias (la tos, los resfriados, gripe,...) en invierno
- Reducción de la gravedad o de la duración de la tos, los resfriados y dolencias de invierno
- Reducción de la posibilidad de infección en ambientes de "alto riesgo" (aviones, áreas urbanas)

Las tecnologías adecuadas pueden ser físicas, químicas o biológicas.
Són de interés tecnologías en todas las fases de desarrollo (pruebas de laboratorio, los ensayos clínicos, los productos comerciales). Leer más

D-237empresa anónima / Reino Unido

1097

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OTC Transdermal and Transmucosal Delivery

transdermal, transmucosal, Drug, Delivery, OTC

Resultado deseado

An international Pharma products group with offices in the UK is seeking technologies and approaches that enable the systemic delivery of common OTC medications for treating typical self-limiting illnesses including aches, incidental pain, colds and flu via transdermal and transmucosal routes, to provide at least 1 of the following benefits:
• Faster acting
• Longer lasting
• Lower dose of active ingredient(s) required

26/08/10 - El deadline de esta demanda ha caducado

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Detalles de la demanda :

Background
The majority of consumer products focused on the treatment and relief from common aches, incidental pain, colds and flu are delivered orally, which may result in reduced speed of action due to digestion and associated metabolic action, as well as being somewhat inconvenient and unpleasant to take.

Technologies and approaches are sought that enable treatments to be delivered to the consumer in a convenient and easy to use format, that also offer the potential benefits of being faster acting, lower dose and/or longer lasting.

Technical Requirements
Transdermal and transmucosal (buccal/sublingual) delivery present several challenges:

• Most active ingredients are large molecules, with some being acidic in nature and having poor water solubility
• It is necessary to be able to deliver 5-50mg of active within 15 minutes
• The active ingredient must permeate the skin into the bloodstream, without causing irritation
• Buccal/sublingual delivery mechanisms need to address potential taste issues, deal with a mucosal and salival environment and not get washed away
• The approach may require permeation ingredients to help the active reach the bloodstream, either paracellularly (to avoid lipid interference in the tissues) or through the cell membranes themselves.

The target is therefore to access technologies and approaches that can successfully deliver against these challenges, providing new or improved benefits vs. current approaches. Products already on the market for the treatment of common aches, incidental pain, colds and flu, or technologies that deliver topical or localised benefits only are not sought.

It would be advantageous to also demonstrate the following:
•In-vivo data that shows correlation with in-vitro studies – to demonstrate the action of the solution.

The materials should also meet the following requirements for incorporation into a consumer product:

1) Compatible with typical OTC Pharmaceutical product packaging and expected to be stable under global ambient temperature and humidity conditions for a period of 2 years.
2) Not require storage or handling under special or inert conditions, e.g. under nitrogen or under oil.
3) Soluble or readily dispersed in the formulations and not negatively affect or interfere with the properties of other components in the formulation.
4) Technologies must be capable of withstanding any process stresses e.g. temperature without chemical degradation or any adverse effects
5) Able to be able to be incorporated into current products using simple batch mixing at room temperature and atmospheric pressure with minimal heating/cooling and no or minimal changes required to current clean down processes.
6) Cost appropriate for consumer products (when incorporated at the required level). As examples, this means maximum £20/kg (GBP) for an ingredient incorporated at 1-5%, and maximum £250/kg (GBP) for an ingredient incorporated at <0.1%
7) Technology must not reduce the existing quality of the user’s experience e.g. poor taste, smell etc.
8) Not be harmful for human use (not classified or suspected to be a toxin, carcinogen, mutagen, irritating to the human respiratory system) with respect to the concentrations used in the final product. Not harmful to the environment (including not being a photo-reactive volatile organic compound).
9) Ideally offer scope for patent protection with the desired application and format.
10) Ingredients must meet the required pharmacopoeia or monograph (i.e. Ph.Eur, USP) and supported under REACh where applicable.
11) Must not appear on these restricted substance lists :
• OSPAR (http://www.ospar.org/v_substances/browse.asp?menu=00950304450072_000000_000000)
• DLUS(http://www.mst.dk/default.asp?Sub=http://www.mst.dk/udgiv/Publications/2000/87-7944-277-3/html/default _eng.htm)
• Proposition 65 (http://www.prop65news.com/pubs/brochure/madesimple.html).

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D-494empresa anónima / Brasil

1830

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Buscamos diagnósticos virales y bacterianos para infecciones del tracto respiratorio superior

Diagnostic, virus, bacteria, Kit, disposable, Healthcare, respiratoy, test, detection, portable, flu

Resultado deseado

Una compañía internacional de healthcare está buscando tecnologías de diagnóstico para que los profesionales de la salud, farmacéuticos, enfermeras, o los propios pacientes puedan realizar una prueba rápida cuando aparecen síntomas relacionados con el tracto respiratorio superior

12/12/12 - El deadline de esta demanda ha caducado

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Detalles de la demanda :

Technologies/Tests/Processes able to provide one of the following from a ‘patient’:

1. Bacterial Infection Diagnosis – Able to determine the presence of a (non-specific) bacterial infection through sample testing (usually blood or saliva, but could be others).

2. Viral (cold & flu based) Infection Diagnosis – Able to determine the presence of a specific viral infection through a saliva sample. Viruses that represent the highest level of incidence: Rhinovirus, Coronavirus, Adenovirus, Respiratory Syncytial and Flu A/B.

3. Strep A Infection Diagnosis – A specific class of the bacterial test above. Strep A tests already exist, and the need here is to improve considerably the ease-of-use, sampling and increased specificity and selectivity.

4. Flu A/B Infection Diagnosis – A specific class of the viral test above. Flu A/B tests are very useful, especially during outbreaks, but are currently too complex for ease-of-use.

Tests should ideally be in a platform that allows ease of use by Healthcare Professionals (Mandatory), Pharmacists / Nurses (Preferred) and consumers (Desirable). It is expected that the platform will be based on conventional Lateral Flow Device technology (LFD), but the company is open to other formats.

Tests should preferably be all-in-one, one use and disposable. The potential for an electronic reader is viable, but cost implications may make this route a challenge.

Tests should be of the disposable kind (low cost) and not require specialist (expensive) instrumentation to read/analyse, should provide results within a 10 minute window and be easy to use. Leer más

D-754empresa anónima / Brasil

1833

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Buscando tecnologías para reconstruir el sistema immunitario y recuperarse más rápidamente de una enfermedad

Healthcare, immunity, recover, virus, infection, cough, flu, Alternative, medicine, supplement

Resultado deseado

An international healthcare group is seeking technologies and approaches that help build immunity and recover faster from an illness, thereby reducing chances of a subsequent infection or relapse
Potential technologies would include chemical, physical or biological methods/ingredients that help in removal of the viral infection from the body, reducing the “load” on the immune system and helping it recover quicker. Alternative approaches could be those that “up-regulate” the bodies innate immune system.

Large healthcare organisation, with several market leader brands and with presence in different countries around the world. More than 25,000 employees and large R&D investment.

20/05/13 - El deadline de esta demanda ha caducado

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Detalles de la demanda :

Un grupo internacional de la salud está buscando tecnologías y enfoques que ayuden a reconstruir el sistema immunitario y recuperarse más rápidamente de una enfermedad, lo que reduce las posibilidades de una infección subsecuente o recaída.
Las posibles tecnologías incluirían químicos, físicos o biológicos / ingredientes que ayudan en la eliminación de la infección viral del cuerpo, reduciendo la "carga" en el sistema inmunológico y ayudar a recuperarse más rápido. Los enfoques alternativos podrían ser los aumentan el sistema inmune innato del cuerpo. Leer más

Innovación en flu : Oportunidades ... | Demandas

Innovación en flu : Oportunidades ... | Demandas

Envía tu propuesta>> Compartir demanda>> En busca de un protector para la tos, resfriados y la gripe estacional

cough, cold, flu, winter disease, OTC, prevention disease products, protection winter ailments

Envía tu propuesta>> Compartir demanda>> OTC Transdermal and Transmucosal Delivery

transdermal, transmucosal, Drug, Delivery, OTC

Envía tu propuesta>> Compartir demanda>> Buscamos diagnósticos virales y bacterianos para infecciones del tracto respiratorio superior

Diagnostic, virus, bacteria, Kit, disposable, Healthcare, respiratoy, test, detection, portable, flu

Una compañía internacional de healthcare está buscando tecnologías de diagnóstico para que los profesionales de la salud, farmacéuticos, enfermeras, o los propios pacientes puedan realizar una prueba rápida cuando aparecen síntomas relacionados con el tracto respiratorio superior

Envía tu propuesta>> Compartir demanda>> Buscando tecnologías para reconstruir el sistema immunitario y recuperarse más rápidamente de una enfermedad

Healthcare, immunity, recover, virus, infection, cough, flu, Alternative, medicine, supplement

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Envía tu propuesta>> Compartir demanda>>
En busca de un protector para la tos, resfriados y la gripe estacional

Envía tu propuesta>> Compartir demanda>>
OTC Transdermal and Transmucosal Delivery

Envía tu propuesta>> Compartir demanda>>
Buscamos diagnósticos virales y bacterianos para infecciones del tracto respiratorio superior

Envía tu propuesta>> Compartir demanda>>
Buscando tecnologías para reconstruir el sistema immunitario y recuperarse más rápidamente de una enfermedad